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|Color:||Yellow Powder||Source:||Rosemary Extract|
|Name:||Ursolic Acid||Another Specification:||Carnosic Acid|
Ursolic Acid Concentrated Plant Extract 77-52-1 Rosemary extract Carnosic Acid rosmarinic acid Skin care Preservation
|Product name||Ursolic acid||Specification||Ursolic acid(25-98%)HPLC|
|Source||Rosemary plant or Loquat leaf||CAS NO||77-52-1|
|Solubility||Good solubility in ethanol||Color||White powder(Ursolic acid 98%)|
|EINECS||201-034-0||Melting point||283-285 ºC|
|Molecular Weight||456.71||Alpha||59 º (c=0.3, pyridine)|
Chemistry: Ursolic acid [(3)-3-Hydroxyurs-12-en-28-oic acid] rarely occurs without its isomer oleanolic acid [(3)-3-Hydroxyolean-12-en-28-oic acid] They may occur in their free acid form, or as aglycones for triterpenoid saponins which are comprised of a triterpenoid aglycone linked to one or more sugar moieties. Ursolic and oleanolic acids are similar in pharmacological activity.
Toxicity: Notwithstanding its numerous cosmetic properties, ursolic acid is an ideal cosmetic ingredient because its overall toxicity (both chronic and acute) is low. It is not a primary irritant or sensitizer. In fact, it has been termed dermatologically innocuous.
Ursolic acid is a pentacyclic triterpene acid, used in cosmetics, that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor.
Ursolic acid is also known as Prunol, Malol, Urson, beta-Ursolic acid, NSC4060, CCRIS 7123, CHEBI:9908, TOS-BB-0966, and 3beta-Hydroxyurs-12-en-28-oic acid. As medicine it is well tolerated and can be used topically and orally.
Ursolic acid is present in many plants, including apples, basil, bilberries, cranberries, elder flower, peppermint, lavender, oregano, thyme, hawthorn, prunes.
Contemporary scientific research which led to the isolation and identification of ursolic acid revealed and confirmed that several pharmacological effects,
1.such as antitumor, hepatoprotective,
2.anti-inflammatory (oral and topical),
4.anti-hyperlipidemic, sedation, antioxidation and antiviral,
5.hair growth stimulant,can be attributed to ursolic acid which is widely used in medicine.It can inhibit Elastase.
6.However, its anti-inflammatory (topical), antitumor (skin cancer), and antimicrobial properties make it useful in cosmetic applications.
How to take ursolic acid?
The only dose from which to work from is 10mg/kg bodyweight.
Note: Do not confuse with usnic acid
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